Assess baseline hematologic (hemoglobin and hematocrit) and iron storage parameters (serum iron, total iron binding capacity, and percent saturation of transferrin) to monitor response to therapy. <> Parenteral iron administration may be associated with hypersensitivity reactions [see Warnings and Precautions (5.1)], which may have serious consequences, such as fetal bradycardia (see Clinical Considerations). Administer the test dose at a gradual rate over at least 30 seconds. . Thank you for submitting a comment on this article. Stability of injectable medications after reconstitution Children weighing 59 kg (1121 lbs): Maximum daily dosage is 50 mg of iron. Do not mix with other drugs or add to parenteral nutrition solutions for IV infusion. Fatal reactions have occurred following a test dose of iron dextran and also in patients in whom the test dose was tolerated. If undiluted, administer by slow IV injection at 50 mg/minute (1 mL/minute). 0000013099 00000 n
Table 1: Total Infed Requirement for Hemoglobin Restoration and Iron Stores Replacement in Patients with Iron Deficiency Anemia*. Curr Opin Clin Nutr Metab Care. INFeD is indicated for treatment of adult and pediatric patients of age 4 months and older with documented iron deficiency who have intolerance to oral iron or have had an unsatisfactory response. INFeD (iron dextran injection), for intravenous or . %%EOF
HHS Vulnerability Disclosure, Help Copyright 2021 GlobalRPH - Web Development by, IV Dilutions Medication Reference and Infusion Guidelines, Renal dosing for healthcare professionals, HONcode standard for trust- worthy health, 7 Natural Remedies for Rheumatoid Arthritis, How Prenatal Counseling Can Help You Through Pregnancy. Blood volume . Calculate the Infed dose based upon the formula below which is based upon the approximate amount of blood loss and pretreatment hematocrit. The physicochemical and mi-crobiological qualities of biological products are functions of the aseptic Use with caution in patients with a history of clinically important allergies and/or asthma. Ferentino, Italy 03013, Distributed By: The half-life of total iron, including both circulating and bound, is approximately 20 hours. Federal government websites often end in .gov or .mil. Ling J, Gupta VD. Stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition mixtures. 0000004233 00000 n
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